1st League 2010/11
| Round | Day | Date | Time | Home Team | Away Team | Result |
| Jeseň |
| 1 | Sunday | July 18, 2010 | 17.30 | MFK Zemplín Michalovce - | MFK Ružomberok B | 2 : 2 (0:1) |  |
| 2 | Sunday | July 25, 2010 | 17.30 | FK Bodva Moldava nad Bodvou - | MFK Ružomberok B | 0 : 0 | |
| 3 | Sunday | August 1, 2010 | 10.30 | MFK Ružomberok B - | MFK Rimavská Sobota | 1 : 0 (0:0) |  |
| 4 | Sunday | August 8, 2010 | 10.30 | MFK Tatran AOS L. Mikuláš - | MFK Ružomberok B | 2 : 0 (1:0) |  |
| 5 | Sunday | August 15, 2010 | 10.30 | MFK Ružomberok B - | FK Slovan Duslo Šaľa | 1 : 1 (0:0) | |
| 6 | Monday | August 23, 2010 | 17.30 | ŠK SFM Senec - | MFK Ružomberok B | 3 : 0 (1:0) | |
| 7 | Sunday | August 29, 2010 | 10.30 | MFK Ružomberok B - | FC Petržalka 1898 | 1 : 1 (0:0) | |
| 8 | Sunday | September 12, 2010 | 15.30 | AS Trenčín - | MFK Ružomberok B | |  |
| 9 | Sunday | September 19, 2010 | 10.30 | MFK Ružomberok B - | FK Púchov | | |
| 10 | Sunday | September 26, 2010 | 10.30 | LAFC Lučenec - | MFK Ružomberok B | | |
| 11 | Sunday | October 3, 2010 | 10.30 | MFK Ružomberok B - | MFK Dolný Kubín | | |
| 12 | Sunday | October 17, 2010 | 10.30 | MFK Ružomberok B - | MFK Zemplín Michalovce | | |
| 13 | Sunday | October 24, 2010 | 10.30 | MFK Ružomberok B - | FK Bodva Moldava nad Bodvou | | |
| 14 | Sunday | October 31, 2010 | 14.00 | MFK Rimavská Sobota - | MFK Ružomberok B | | |
| 15 | Sunday | November 7, 2010 | 10.30 | MFK Ružomberok B - | MFK Tatran AOS L. Mikuláš | | |
| 16 | Sunday | November 14, 2010 | 13.30 | FK Slovan Duslo Šaľa - | MFK Ružomberok B | | |
| 17 | Sunday | November 21, 2010 | 10.30 | MFK Ružomberok B - | FC Senec | | |
| 18 | Sunday | November 28, 2010 | 10.30 | FC Petržalka 1898 - | MFK Ružomberok B | | |